Prof. James Di Santo received MD and PhD degrees from Cornell Medical College and the Sloan Kettering Institute in New York and completed postdoctoral training with Pr Alain Fischer (Necker Hospital, Paris, France) and Pr Klaus Rajewsky (Institute for Genetics, Cologne, Germany). In 1999, he created his own lab at the Institut Pasteur in Paris where he currently holds the position of Professor in the Immunology Department and Research Director within the French Medical Research Institute (Inserm).

Pr. Di Santo’s main scientific interests are in the areas of lymphocyte biology, cytokines, transcription factors, and signaling pathways in the development and function of both adaptive (T and B cell) and innate (ILC, NK cells) lymphocytes in mice and man. His laboratory has developed a series of human immune system mouse models that allow for an in-depth analysis of human immunity in a pre-clinical setting, with applications for the treatment of human infectious diseases. More recently, he has developed an integrated systems immunology approach using nasal swab samples to assess human mucosal immunity in healthy individuals and in patients suffering from respiratory diseases that will be applied in the context of the Pasteur International Research Unit ‘Mucosal Immunomics’ with Pr. Ken Ishii (International Vaccine Design Center, IMSUT).